Understanding how and why damaged cells develop into cancers is the focus of recently published research by Walter and Eliza Hall Institute scientists.
The development of cells from their normal state to that of a malignant tumour is known as ‘neoplastic transformation’, a process driven by DNA lesions. During neoplastic transformation cells acquire the ability to evade apoptosis, a process of programmed cell death, and the ability to divide uncontrollably.
Cancer cells ignore the body’s tumour suppressive signals to stop dividing and to kill off unneeded cells. Read more about this story here.